Poppers is the street term for various alkyl nitrites taken for recreational purposes through direct inhalation[1], particularly amyl nitrite, butyl nitrite and isobutyl nitrite.[2][3] Amyl nitrite has a centuries-long history of safe use in treating angina,[1] as well as an antidote to cyanide poisoning.[4][5] Amyl nitrite and several other alkyl nitrites which are used in over-the-counter products, such as air fresheners and video head cleaners, may be inhaled to enhance sexual pleasure.[6] Use is particularly prominent among urban gay men.[6] These products have long been part of the club culture from the 1970s disco scene to the 1980s and 1990s rave scene.[7]