General
Much of the problem in arriving at a consensus relates to a failure to adopt generally agreed-on definitions[42] or research methodology. Research has used highly selected individuals, case studies, or very small numbers of subjects, making generalization difficult. For instance, much of the research into the nature of the fluid focuses on determining whether it is or contains urine. There are also problems involved in the collection of specimens and issues of contamination. Since the area of interest is para-urethral glands, it is impossible to completely separate the secretions from urine, especially considering that there may be retrograde ejaculation into the urethra towards the bladder. The best current data comes from studies where women have abstained from coitus, and where their own urine is used as a control both pre- and post-orgasm. Research has attempted to use chemicals that are excreted in the urine so that any urinary contamination can be detected. Further methodological issues include the fact that the composition of the fluid appears to vary with the menstrual cycle,[43] and that the biochemical profile of the para-urethral tissues varies with age.[44] Other issues relate to the sensitivity and specificity of the markers chosen. The key questions are the source of the fluid produced, and its composition.
Nature of fluid
Critics have maintained that ejaculation is either stress incontinence or vaginal lubrication. Research in this area has concentrated almost exclusively on attempts to prove that the ejaculate is not urine,[48][49] measuring substances such as urea, creatinine, prostatic acid phosphatase (PAP), prostate specific antigen (PSA),[7] glucose and fructose [50] levels. Early work was contradictory; the initial study on one woman by Addiego and colleagues reported in 1981,[30] could not be confirmed in a subsequent study on 11 women in 1983, [51] but was confirmed in another 7 women in 1984.[52] In 1985 a different group studied 27 women, and found only urine,[53] suggesting that results depend critically on the methods used.[citation needed]
A 2007 study on two women involved ultrasound, endoscopy, and biochemical analysis of fluid. The ejaculate was compared to pre-orgasmic urine from the same woman, and also to published data on male ejaculate. In both women, higher levels of PSA, PAP, and glucose but lower levels of creatinine were found in the ejaculate than the urine. PSA levels were comparable to those in males.
You wont know, until you try!